USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q99439 USC-OGP 2-DE database:  Q99439 Q99439 General information about the entry View entry in simple text format Entry name CNN2_HUMAN Primary accession number Q99439 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Calponin-2; AltName: Full=Calponin H2, smooth muscle; AltName: Full=Neutral calponin;. Gene name Name=CNN2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0460: pI=6.77; Mw=34145 SPOT OGP-0461: pI=6.26; Mw=34062 SPOT OGP-0462: pI=6.31; Mw=33979 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0979: pI=6.72; Mw=33957 SPOT OGP-0981: pI=6.29; Mw=33441 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1202: pI=5.22; Mw=39342 SPOT OGP-1232: pI=6.94; Mw=33797 SPOT OGP-1238: pI=7.05; Mw=32952 Cross-references UniProtKB/Swiss-Prot Q99439; CNN2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CNN2_HUMAN Primary accession number Q99439 Secondary accession number(s) A5D8U8 A6NFI4 D6W5X9 Q92578 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Calponin-2; AltName: Full=Calponin H2, smooth muscle; AltName: Full=Neutral calponin; Gene name Name=CNN2 Encoded on Name=CNN2 Keywords 3D-structure; Acetylation; Actin-binding; Alternative splicing; Calmodulin-binding; Complete proteome; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D83735; BAA12090.1; -; mRNA EMBL AK126391; BAG54322.1; -; mRNA EMBL AC004528; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC011558; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471139; EAW69565.1; -; Genomic_DNA EMBL CH471139; EAW69567.1; -; Genomic_DNA EMBL CH471139; EAW69570.1; -; Genomic_DNA EMBL BC141818; AAI41819.1; -; mRNA EMBL BC141833; AAI41834.1; -; mRNA EMBL D86059; BAA20887.1; -; mRNA CCDS CCDS12053.1; -. [Q99439-1]; . CCDS CCDS12054.1; -. [Q99439-2]; . PIR JC4906; JC4906; . RefSeq NP_001290428.1; NM_001303499.1; . RefSeq NP_001290430.1; NM_001303501.1; . RefSeq NP_004359.1; NM_004368.3. [Q99439-1]; . RefSeq NP_958434.1; NM_201277.2. [Q99439-2]; . UniGene Hs.651512; -; . PDB 1WYN; NMR; -; A=20-152 PDBsum 1WYN; -; . ProteinModelPortal Q99439; -; . SMR Q99439; -; . BioGrid 107665; 25; . IntAct Q99439; 5; . STRING 9606.ENSP00000263097; -; . iPTMnet Q99439; -; . PhosphoSitePlus Q99439; -; . SwissPalm Q99439; -; . BioMuta CNN2; -; . DMDM 6226844; -; . OGP Q99439; -; . EPD Q99439; -; . MaxQB Q99439; -; . PaxDb Q99439; -; . PeptideAtlas Q99439; -; . PRIDE Q99439; -; . DNASU 1265; -; . Ensembl ENST00000263097; ENSP00000263097; ENSG00000064666. [Q99439-1]; . Ensembl ENST00000348419; ENSP00000340129; ENSG00000064666. [Q99439-2]; . GeneID 1265; -; . KEGG hsa:1265; -; . UCSC uc002lqu.4; human. [Q99439-1]; . CTD 1265; -; . DisGeNET 1265; -; . GeneCards CNN2; -; . HGNC HGNC:2156; CNN2; . HPA HPA049095; -; . MIM 602373; gene; . neXtProt NX_Q99439; -; . OpenTargets ENSG00000064666; -; . PharmGKB PA26666; -; . eggNOG KOG2046; Eukaryota; . eggNOG COG5199; LUCA; . GeneTree ENSGT00550000074447; -; . HOGENOM HOG000232113; -; . HOVERGEN HBG005186; -; . InParanoid Q99439; -; . PhylomeDB Q99439; -; . TreeFam TF313921; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS CNN2; human; . EvolutionaryTrace Q99439; -; . GenomeRNAi 1265; -; . PRO PR:Q99439; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000064666; -; . CleanEx HS_CNN2; -; . ExpressionAtlas Q99439; baseline and differential; . Genevisible Q99439; HS; . GO GO:0005911; C:cell-cell junction; TAS:ProtInc; . GO GO:0005856; C:cytoskeleton; TAS:ProtInc; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0035580; C:specific granule lumen; TAS:Reactome; . GO GO:0001725; C:stress fiber; IDA:MGI; . GO GO:1904724; C:tertiary granule lumen; TAS:Reactome; . GO GO:0003779; F:actin binding; TAS:ProtInc; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0031032; P:actomyosin structure organization; IEA:InterPro; . GO GO:0071260; P:cellular response to mechanical stimulus; IDA:MGI; . GO GO:0007010; P:cytoskeleton organization; TAS:ProtInc; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0032970; P:regulation of actin filament-based process; IDA:MGI; . CDD cd00014; CH; 1; . Gene3D 1.10.418.10; -; 1; . InterPro IPR001997; Calponin/LIMCH1; . InterPro IPR000557; Calponin_repeat; . InterPro IPR001715; CH-domain; . InterPro IPR029974; CNN2; . InterPro IPR003096; SM22_calponin; . PANTHER PTHR18959:SF71; PTHR18959:SF71; 1; . Pfam PF00402; Calponin; 3; . Pfam PF00307; CH; 1; . PRINTS PR00889; CALPONIN; . PRINTS PR00888; SM22CALPONIN; . SMART SM00033; CH; 1; . SUPFAM SSF47576; SSF47576; 1; . PROSITE PS01052; CALPONIN_1; 3; . PROSITE PS51122; CALPONIN_2; 3; . PROSITE PS50021; CH; 1; .

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